Introduction:

Introduction

Stuart B. Goodman and Timothy Wright
J Am Acad Orthop Surg 2008 16: x. [Full Text] [PDF]  

Dedication:

Seppo Santavirta: The Life and Work of an Orthopaedic Surgeon and Scientist. A Tribute From His Friends

Yrjö T. Konttinen, Stuart B. Goodman, and Timothy Wright
J Am Acad Orthop Surg 2008 16: xii. [Full Text] [PDF]  

Clinical Questions:

How prevalent are implant wear and osteolysis, and how has the scope of osteolysis changed since 2000?

Amanda Marshall, Michael D. Ries, and Wayne Paprosky
J Am Acad Orthop Surg 2008 16: S1-S6. [Abstract] [Full Text] [PDF]  

What patient and surgical factors contribute to implant wear and osteolysis in total joint arthroplasty?

Audrey K. Tsao, Lynne C. Jones, and David G. Lewallen
J Am Acad Orthop Surg 2008 16: S7-S13. [Abstract] [Full Text] [PDF]  

How are wear-related problems diagnosed and what forms of surveillance are necessary?

Henrik Malchau and Hollis G. Potter
J Am Acad Orthop Surg 2008 16: S14-S19. [Abstract] [Full Text] [PDF]  

What are the guidelines for the surgical and nonsurgical treatment of periprosthetic osteolysis?

Bernard N. Stulberg and Alejandro González Della Valle
J Am Acad Orthop Surg 2008 16: S20-S25. [Abstract] [Full Text] [PDF]  

What is the outcome of treatment for osteolysis?

William Maloney and Aaron Rosenberg
J Am Acad Orthop Surg 2008 16: S26-S32. [Abstract] [Full Text] [PDF]  

How have alternative bearings (such as metal-on-metal, highly cross-linked polyethylene, and ceramic-on-ceramic) affected the prevention and treatment of osteolysis?

John J. Callaghan, John M. Cuckler, James I. Huddleston, and Jorge O. Galante
J Am Acad Orthop Surg 2008 16: S33-S38. [Abstract] [Full Text] [PDF]  

Clinical Issues Summary

Thomas P. Sculco, John J. Callaghan, and Jorge O. Galante
J Am Acad Orthop Surg 2008 16: S39-S40. [Full Text] [PDF]  

Biologic Questions:

What are the local and systemic biologic reactions and mediators to wear debris, and what host factors determine or modulate the biologic response to wear particles?

Rocky S. Tuan, Francis Young-In Lee, Yrjö T. Konttinen, J. Mark Wilkinson, and Robert Lane Smith
J Am Acad Orthop Surg 2008 16: S42-S48. [Abstract] [Full Text] [PDF]  

How has the biologic reaction to wear particles changed with newer bearing surfaces?

Joshua J. Jacobs, Patricia A. Campbell, and Yrjö T. Konttinen
J Am Acad Orthop Surg 2008 16: S49-S55. [Abstract] [Full Text] [PDF]  

What other biologic and mechanical factors might contribute to osteolysis?

Ed M. Greenfield and Joan Bechtold
J Am Acad Orthop Surg 2008 16: S56-S62. [Abstract] [Full Text] [PDF]  

What experimental approaches (eg, in vivo, in vitro, tissue retrieval) are effective in investigating the biologic effects of particles?

Mathias Bostrom and Regis O’Keefe
J Am Acad Orthop Surg 2008 16: S63-S67. [Abstract] [Full Text] [PDF]  

Are there biological markers of wear?

Thomas W. Bauer and Arun S. Shanbhag
J Am Acad Orthop Surg 2008 16: S68-S71. [Abstract] [Full Text] [PDF]  

What potential biologic treatments are available for osteolysis?

Edward M. Schwarz
J Am Acad Orthop Surg 2008 16: S72-S75. [Abstract] [Full Text] [PDF]  

Biology Summary

Stuart B. Goodman, Victor Goldberg, and Regis O’Keefe
J Am Acad Orthop Surg 2008 16: S76-S78. [Full Text] [PDF]  

Engineering Questions:

How have new sterilization techniques and new forms of polyethylene influenced wear in total joint replacement?

Roy D. Crowninshield and Orhun K. Muratoglu
J Am Acad Orthop Surg 2008 16: S80-S85. [Abstract] [Full Text] [PDF]  

How do alternative bearing surfaces influence wear behavior?

Ian C. Clarke and Michael T. Manley
J Am Acad Orthop Surg 2008 16: S86-S93. [Abstract] [Full Text] [PDF]  

How do material properties influence wear and fracture mechanisms?

Clare Rimnac and Lisa Pruitt
J Am Acad Orthop Surg 2008 16: S94-S100. [Abstract] [Full Text] [PDF]  

What design factors influence wear behavior at the bearing surfaces in total joint replacements?

Thomas D. Brown and Donald L. Bartel
J Am Acad Orthop Surg 2008 16: S101-S106. [Abstract] [Full Text] [PDF]  

How have new designs and new types of joint replacement influenced wear behavior?

Steven M. Kurtz and Peter S. Walker
J Am Acad Orthop Surg 2008 16: S107-S110. [Abstract] [Full Text] [PDF]  

How have wear testing and joint simulator studies helped to discriminate among materials and designs?

Harry A. McKellop and Darryl D’Lima
J Am Acad Orthop Surg 2008 16: S111-S119. [Abstract] [Full Text] [PDF]  

Engineering Summary

Timothy Wright, A. Seth Greenwald, Jack Lemons, and Ebru Oral
J Am Acad Orthop Surg 2008 16: S120-S121. [Full Text] [PDF]  

US Food and Drug Administration: The Regulatory Process and Frequently Asked Questions:

Orthopaedic Joint Devices: The FDA’s Short Answers to Your Questions

Jonette R. Foy and Barbara D. Buch
J Am Acad Orthop Surg 2008 16: S123-S128. [Abstract] [Full Text] [PDF] [Supplementary Table]  

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